Immunotherapy treatment is based on a century-old concept that the immune system can be desensitized to specific allergens that trigger allergy symptoms. These
symptoms may be caused by allergic respiratory conditions such as allergic rhinitis and asthma.
Immunotherapy can potentially lead to lasting remission of allergy symptoms, and it may play a preventive role in terms of development of asthma, nasal polyps and new allergies.
The Immunotherapy Process
Sublingual immunotherapy has emerged as an effective and safer alternative to the subcutaneous route for both seasonal and perennial disease. Sublingual immunotherapy has also been shown to have long-term benefits has the big advantage of self-administration in the patient’s home.
What is the treatment duration?
Most patients will require 3-5 years of treatment to ensure good long term remission of allergies
How do I know treatment is effective?
Immunotherapy for allergic rhinitis
The first results are visible after completing the first year of treatment. The best measure of successful treatment is the reduction in symptoms and the need for nasal sprays and antihistamines.
References
- Petalas K, Durham SR. Allergen immunotherapy for allergic rhinitis. Rhinology. 2013 Jun;51(2):99-110.
- Möbs C, Slotosch C, Löffler H, Jakob T, Hertl M, Pfützner W. Birch pollen immunotherapy leads to differential induction of regulatory T cells and delayed helper T cell immune deviation. J Immunol. 2010 Feb 15;184(4):2194-203.
- Möbs C, Ipsen H, Mayer L, Slotosch C, Petersen A, Würtzen PA, Hertl M, Pfützner W. Birch pollen immunotherapy results in long-term loss of Bet v 1-specific TH2 responses, transient TR1 activation, and synthesis of IgE-blocking antibodies. J Allergy Clin Immunol. 2012 Nov;130(5):1108-1116.e6.
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